The body has several physical barriers to “outside” threats, the skin, the respiratory linings and the digestive tract. Of these three, the digestive tract faces the most potential threats, not only from what is ingested but also from what develops in situ, through the growth of microorganisms, the toxins some produce and even the remnants of those that die within the tract. Pathogenic bacteria normally exist within the gastrointestinal (GI) tract. Common ones include species of Salmonella and E. coli. Both these bacteria are gram-negative (G-), meaning they have cell walls that will not accept that stain. These bacteria can lyse, and their cell walls are broken into segments that contain “endotoxin” made of lipopolysaccharides (LPS).