The treatment of clinical mastitis has dramatically changed in the approximately 50 years of my veterinary career. The major focus has been on the proper and judicious use of antibiotics in dairy cattle and assuring the public there are no antibiotic residues in the milk supply. 

Among the more problematic pathogens affecting cattle, Mycoplasma bovis (M. bovis) stands out for its involvement in chronic infections. The interaction between the outer makeup of the microorganism and the animal’s immune response contributes to its insidious nature, making treatment as well as prevention difficult.

Antimicrobial resistance is one of the most urgent global health threats and development challenges scientists face today. And dairy is responding with stewardship and materials that advance our industry’s interests in combating the threat.

At recent national and global meetings in September and November, DFC has ensured policy makers learned about the work dairy farmers are doing on antimicrobial usage and what help farmers will need to play their part within a “One Health” approach.

Antimicrobial resistance (AMR) is a top human health risk. It’s something directly affecting farmers and farm workers, who are constantly exposed to bacteria through their livestock.

Over recent decades, cattle disease management, prevention and treatment have changed dramatically. Vaccines, antibiotics, technology and even diseases have altered course.

For the past several years, the U.S. dairy industry has continued to reduce antibiotic and antimicrobial residues in milk and dairy beef. To support producers in the dairy industry’s commitment to antimicrobial stewardship, the FARM Program released its 2024-25 Milk & Dairy Beef Drug Residue Prevention Reference Manual.

When an antibiotic is administered, susceptible bacteria may be eliminated, allowing resistant bacteria to thrive, and become dominant. This can make the antibiotic ineffective for future treatments and can therefore increase the risk of infections persisting in the afflicted animal and spreading to other animals in the herd, or to humans.